Charles P Romano, Ph.D.

Senior Patent Agent

Direct (314) 552-6255

Fax (314) 552-7255

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Dr. Charles Romano is a Senior Patent Agent in the firm’s intellectual property practice area. As a former research Director at Monsanto and Apath, Charles has over fourteen years of experience in the biotech industry. He is a named inventor on sixteen issued United States patents in molecular biology, agricultural biotechnology and pharmaceutical discovery and has published in peer-reviewed scientific journals such as Genes and Development, The Plant Cell, EMBO Journal and PNAS-USA.

Key achievements include leadership of the team that identified the initial Monsanto YieldGard® Rootworm product and acquisition of more than $1 million in Small Business Innovation Research Awards from the National Institutes of Health. Charles prepares and prosecutes biotech and pharmaceutical patent applications before the US Patent and Trademark Office as a registered patent agent.

Apath

Fermalogic

Monsanto

Rockefeller University

Tate & Lyle

University of Missouri

University of Nebraska

University of Tennessee

Washington University in St. Louis

Romano CP, Robson PR, Smith H, Estelle M, Klee H. Transgene-mediated auxin overproduction in Arabidopsis: hypocotyl elongation phenotype and interactions with the hy6-1 hypocotyl elongation and axr1 auxin-resistant mutants Plant Mol Biol. 1995 Mar;27(6):1071-83

Romano CP, Cooper ML, Klee HJ. Uncoupling Auxin and Ethylene Effects in Transgenic Tobacco and Arabidopsis Plants Plant Cell. 1993 Feb;5(2):181-189.

Romano CP, Hein MB, Klee HJ. Inactivation of auxin in tobacco transformed with the indoleacetic acid-lysine synthetase gene of Pseudomonas savastanoi. Genes Dev. 1991 Mar;5(3):438-46.

Romano CP, Bienz-Tadmor B, Mariani BD, Kafatos FC. Both early and late Drosophila chorion gene promoters confer correct temporal,tissue and sex specificity on a reporter Adh gene. EMBO J. 1988 Mar;7(3):783-90.

“Multiple Viral Replicon Culture Systems,” J. Dyall, P. Olivo, R. Roth, C. Romano. U.S. Patent No. 6,750,009; (6/15/2004)

“Expression of Cry3b Insecticidal Protein In Plants,” C. Romano. U.S. Patent No. 6,501,009; (12/31/2002)

“Methods for Transforming Plants to Express Cry2Ab. Delta-Endotoxins Targeted to Plastids,” D. Corbin and C. Romano. U.S. Patent No. 6,489,542; (12/3/2002)

"Nucleic acid sequences from Diabrotica virgifera virgifera LeConte and uses thereof," S. Andersen, G. Hicks, J. Huesing, C. Romano, C. Vetsch. U.S. Patent No. 7,612,194; (11/3/2009)

“A Methods and Compositions for Controlling Insects,” B. Isaac, J. Greenplate, J. Purcell, C. Romano. U.S. Patent No. 6,372,211; (4/16/2002)

“Nucleic Acid Segments Encoding Modified Bacillus Thuringiensis Coleopteran-Toxic Crystal Proteins,” L. English, S. Brussock, T. Malvar, J. Bryson, C. Kulesza, F. Walters, S. Slatin, M. Von Tersch and C. Romano. U.S. Patent No. 6,060,594; (5/9/2000)

“Insect-Resistant Transgenic Plants,” L. English, S. Brussock, T. Malvar, J. Bryson, C. Kulesza, F. Walters, S. Slatin, M. Von Tersch and C. Romano. U.S. Patent No. 6,023,013; (2/8/2000)

Education

Harvard University: Ph.D., Biochemistry (1989)
University of Massachusetts: B.S., Microbiology (1983)

Employment

Thompson Coburn LLP: Senior Patent Agent (2005-Present)
Blackwell, Sanders, Peper, Martin LLP: Biotechnology Advisor (2004)
Proteon Therapeutics, Inc.: Scientific Consultant (2003-2004)
Apath LLC: Director, Antiviral Screening (2001-2003)
Monsanto Company: Various Positions Including Director, Hybridization (1989-2000)